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Job openings

  • PostDoc

Venue: Würzburg University
Date: 30. September 2019

30 September 2019

PhD Canditate and Postdoctoral Reseacher

macromolecular X-ray crystallography, Cryo-EM

for two projects in structural biology methods development, the Thorn Laboratory the Rudolf Virchow Center at the University of Würzburg is looking for a

PHD CANDIDATE (m/f/d)
and a
POSTDOCTORAL RESEARCHER (m/f/d)

Our lab develops new methods for macromolecular X-ray crystallography and Cryo-EM. In these exciting projects you will improve how well we understand, measure and model macromolecular crystal structures using practical experiments and big data analyses. We are looking for candidates with skills in data analysis and programming. Any previous experiences in crystallography, molecular biology, machine learning, image or statistical analysis are also a bonus. You should be a good communicator. For the PhD project, we offer a 36-month full- or part-time position, embedded in the Würzburg Graduate School for Life Sciences (GSLS); for the postdoctoral position, we offer a 30-month full- or part-time position with a competitive salary as well as career and family support. Women are particularly encouraged to apply.

For more details, see:

https://www.uni-wuerzburg.de/fileadmin/43020000/2019/Stellenanzeige_PhD_Thorn_September_2019_final_Auslage.pdf

https://www.uni-wuerzburg.de/fileadmin/43020000/2019/Stellenanzeige_PostdocThorn_Sep_2019_final_Auslage.pdf

https://www.uni-wuerzburg.de/rvz/forschung/assoziierte-forschungsgruppen/ag-thorn/

 

If you have any questions, please email to Dr. Andrea Thorn: andrea.thorn@uni-wuerzburg.de

 

 

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  • PostDoc

Technische Universität Kaiserslautern
17. September 2019
 

17 September 2019

Postdoctoral Position in Membrane Biophysics

research on protein-lipid interactions for one year (possibly with extension)       

The Molecular Biophysics group of Professor Sandro Keller invites applications for a Postdoctoral Position in Membrane Biophysics
initially for one year (possibly with extension) starting as soon as possible.

The research activities of the Keller group lie at the interface of biology, chemistry, and physics, with a particular focus on protein–lipid interactions. More information can be found here: www.bio.uni-kl.de/en/molbiophysik/ag-keller/

Tasks and responsibilities:
The project aims at (1) unravelling the mechanism of action of a human pore-forming protein and (2) testing small-molecule inhibitors of pore formation. This shall be accomplished with the aid of a range of biophysical and biochemical methods, in particular, time-resolved and steady-state fluorescence spectroscopy and electrophysiological experiments using planar lipid bilayers. The postdoctoral fellow is expected to take the lead in a highly competitive research project involving academic and industrial collaborators, write publications, and give oral presentations at international conferences.

Qualifications:
We are looking for a highly motivated postdoctoral fellow with
• a PhD in molecular biology, chemistry, physics, or related fields
• expertise in membrane biophysics or biochemistry, ideally of pore-forming proteins
• experience with optical spectroscopy or planar lipid bilayers
• a strong publication record
• the ability to work independently and in teams
• proficiency in written and spoken English
Application
Applications must be in English and include the following information in a single PDF:
• a motivation letter (max. two pages)
• a curriculum vitae (max. two pages)
• a list of publications


Please e-mail your application to mailto: sandro.keller@biologie.uni-kl.de as soon as possible.

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  • Professorship

Utrecht University, Netherlands
03 September 2019

03 September 2019

Open Positions in Chemistry

at a world class center of research and education in Utrecht, Netherlands           

 

The Department of Chemistry (https://www.uu.nl/en/organisation/department-of-chemistry) at Utrecht University in the Netherlands is renowned as a world class center of excellence and innovation in both research
and education, fully resourced and equipped with state-of-the-art technological platforms.
Our approach is characterized by a connected, open and can-do spirit that stimulates personal initiative and curiosity. You are encouraged to take ownership and create value while sharing your knowledge both internally and across the wider (global) research community. We strive every day to enable this mission because we know it is the only way to make the breakthroughs that will help to solve the challenges facing the world.
Meaningful opportunities in life sciences and sustainability. The Department is growing and actively recruiting new staff members for our two core areas of fundamental research – molecular level life science research and nanomaterials research for sustainability. This research takes place within two advanced and future-focused facilities:


• The Bijvoet Center https://www.uu.nl/en/research/bijvoet-center-for-biomolecular-research advances our understanding of life at the most detailed molecular level by using cuttingedge structural and analytical methods in combination with state-of-the-art molecular biology, biochemistry as well as biophysical methods. This has the potential to help us understand the cause of diseases in a fundamental way.
• The Debye Institute https://www.uu.nl/en/research/debye-institute-for-nanomaterials-science for Nanomaterials Science tackles sustainability through research into catalysis, nanostructures and colloids, and nanophotonics.
This has the potential to yield valuable sustainability benefits for opto-electronic applications such as LEDs and miniaturized lasers, and advanced catalytic applications such as biomass valorization and small molecule activation.

Interested in joining us?
We’d love to hear from you if you have a broad research background in either of these areas and would like to be part of this stimulating and diverse environment. We are particularly interested in hearing from female scientists worldwide who contribute their skills and curiosity to our inclusive approach to life and work.

Utrecht University: Enjoy a great work-life balance in
a wonderful city

Utrecht is an attractive city located in the heart of the Netherlands, one of the world’s most open and connected countries. Utrecht University reflects this philosophy by offering a flexible work/life balance that prioritizes your well-being within an understanding and supportive, international environment.

Open positions in Chemistry:
Associate/ Full professor: Mapping the in-vivo molecular landscape
Developing a research program that studies the impact of the overall organization and function of molecules on spatio-temporal processes in cells and tissue.

Assistant/ Associate professor: Dynamic organization in native membranes
Developing a research program that studies and manipulates interactions between membrane components and proteins under physiological conditions.

Assistant/ Associate professor: Conformational switches in regulation
Developing genetic, chemical, and computational tools to probe and manipulate protein dynamics relevant for function on a cellular level.

Associate/ Full professor: Quantum chemical modelling
Contribute to a sustainability research program that models hybrid organic/inorganic interfaces on the nanoscale

Assistant/ Associate professor: Quantum chemical simulation
Contribute to a sustainability research program that simulates (charged) catalytic interfaces in batteries.

Assistant/Associate professor: Electron microscopy related to materials and catalysis
Contribute to a catalysis and materials science-oriented research program through an expertise in (in situ) electron microscopy.

 

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  • PostDoc

University of Würzburg
27 August 2019

 

27 August 2019

Post-doctoral Researcher (m/f/d)

in crystallographic methods and software development at the University of Würzburg   

Scope and your role

You will undertake research in the group of Dr. Andrea Thorn to improve the quality of measurements and processing of XFEL, neutron and conventional X-ray diffraction data, to establish major error sources and to define new best practices for macromolecular diffraction experiments. We aim to create new automatic and visual diagnostics by expanding the AUSPEX software (www.auspex.de) using statistical analysis, machine learning and visual data representation. In order to do so, collaboration was set up with four major diffraction facilities in Europe: the BESSY synchrotron in Berlin, the European Spallation Source (ESS) in Lund, the ESRF in Grenoble as well as the European XFEL in Hamburg. You will visit these facilities regularly to develop and implement new diagnostics in close collaboration and publish your results in peer-reviewed journals. Furthermore, you will be expected to contribute to teaching, training, public outreach and to present your work at in-house and international meetings.

What we offer
We offer a 30-month full- or part-time position at the Rudolf-Virchow Center (RVZ) of the University Würzburg, the birthplace of X-rays, with a competitive salary commensurate with your training and experience according to salary agreement TV-L. Your position is funded by the German Federal Ministry of Education and Research (BMBF) as part of the AUSPEX project (press release). This exciting project will allow you to define new quality standards in macromolecular structure determination and to establish a European network in the crystallographic community. Our group is well-connected and AUSPEX is part of the CCP4 suite for macromolecular crystallography. We maintain close ties with other method developers worldwide.


The  RVZ is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including:

  • Research, leadership and management courses
  • Advice, coaching and career support at the JMU Research Academy
  • Courses in teaching within a certified educational training program
  • Career Support at the JMU Academic Staff Development Office
  • Assistance for grant applications from the JMU Research Advancement Centre and the JMU Service Center for Research and Technology Transfer You will have access to both national and the public-service pension schemes (VBL), health care, and 30 days of holiday  entitlement (if working full-time) in addition to 13 annual public holidays in Bavaria. The University also offers access to employee shopping/travel discounts, and there might be cake on occasion. The JMU Welcome Center  supports international candidates with finding accommodation, general information regarding taxes, insurance, healthcare and other administrative matters. The University also offers support for candidates with children, including the University kindergarten, advice regarding school placement, holiday programs and flexible work hours.

Qualification profile
You should have a doctoral degree in a chemical, biological, physical, computational or other relevant subject or be due to complete your doctoral studies within 3 months of applying. You should be able to develop your own ideas, and have the necessary skills to successfully drive and complete a research project, both working independently and as part of a team. We are looking for someone with a good working knowledge of Linux, Python and C++, ideally including common crystallographic libraries such as gemmi, cctbx or clipper. You should be good at statistical data analysis, ideally including experience with the statistical package R. Web-based programming skills (e.g. JavaScript, html5, css), previous experience with machine learning and neural networks are also a bonus. You should have previous experience in crystallography or be willing to learn both its theoretical basis as well as how to conduct crystallographic experiments on the job.
You should be a good communicator, willing to convey complex problems to lay audiences, as well as to instruct and supervise students. An excellent command of English is a prerequisite; German language skills will also be required, but if you do not speak German, we will offer training. Due to the collaborative nature of this project, you should be willing to travel. Female scientists are particularly encouraged to apply! Disabled applicants will be preferentially considered in case of equivalent qualification.

Application
The position will start on 1st October 2019 or later. Applications should be sent by e-mail as one single pdf-document including: cover letter, curriculum vitae (including software projects you contributed to, teaching experience and academic track-record), diplomas/certificates and 3 addresses of referees by 8th September 2019 to

mailto:andrea.thorn@uni-wuerzburg.de

https://www.uni-wuerzburg.de/en/home/

https://www.uni-wuerzburg.de/en/welcomecentre/start-page/

https://www.uni-wuerzburg.de/en/rvz/home/

support for candidates

 

If you have any further questions, please do not hesitate to contact us!

Rudolf-Virchow-Zentrum für Experimentelle Biomedizin der
Universität Würzburg
Dr. Andrea Thorn
Josef-Schneider-Str. 2 / Haus D15
D-97080 Würzburg

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